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The structural stability of the HIV-1 protease

โœ Scribed by Matthew J. Todd; Nora Semo; Ernesto Freire


Book ID
115628767
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
590 KB
Volume
283
Category
Article
ISSN
0022-2836

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The effects of the peptide inhibitor acetyl pepstatin on the structural stability of the HIV-1 protease have been measured by high sensitivity calorimetric techniques. At 25ยฐC and pH 3.6, acetyl pepstatin binds to HIV-1 protease with an affinity of 1.6 ุ‹ 10 7 M -1 and an enthalpy of 7.3 ุŽ 0.5 kcal/m

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