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The structural gene for F liver protein (Flp) maps to chromosome 5 of the mouse

✍ Scribed by G. Winchester; N. A. Mitchison; B. A. Taylor

Publisher: Springer-Verlag
Year: 1987
Tongue: English
Weight: 269 KB
Volume: 26
Category: Article
ISSN: 0093-7711
DOI: 10.1007/bf00343704

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✦ Synopsis

The BXD and AKXL panels of recombinant inbred mouse strains have been typed for the F liver protein alloantigen. The structural gene for F liver protein gene (Flp) is placed on the distal part of chromosome 5, between the known markers Bcd-1 and Gus-s. This excludes the possibility that F liver protein is a major histocompatibility complex molecule, and in turn raises a question about the uniqueness of F and certain other proteins as purgers of self-reactivity among T but not B cells. The typed RI strains have then been used for the immunogenetic studies presented in the succeeding article.

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