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The Structural Context of Disease-causing Mutations in Gap Junctions

✍ Scribed by Fleishman, S. J.; Sabag, A. D.; Ophir, E.; Avraham, K. B.; Ben-Tal, N.


Book ID
118278378
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2006
Tongue
English
Weight
511 KB
Volume
281
Category
Article
ISSN
0021-9258

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Gap junctions are cell junctions found between most cells and tissues. They contain membrane channels that mediate the cell-to-cell diffusion of ions, metabolites, and small cell signaling molecules. Cellcell communication mediated by gap junctions has been proposed to have a variety of functions, i