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The Structural Basis of Ribozyme-Catalyzed RNA Assembly

✍ Scribed by Robertson, M. P.; Scott, W. G.


Book ID
118068512
Publisher
American Association for the Advancement of Science
Year
2007
Tongue
English
Weight
528 KB
Volume
315
Category
Article
ISSN
0036-8075

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Recent studies of the hairpin ribozyme have revealed a distinct catalytic mechanism for this small RNA motif. Inner-sphere coordinated metal ions are not required, as the inert metal ion complex cobalt hexammine promotes catalysis. Detailed kinetic analyses have defined rates of individual steps in