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The structural basis for substrate-induced changes in redox potential and spin equilibrium in cytochrome P-450CAM

✍ Scribed by Raag, Reetta; Poulos, Thomas L.


Book ID
126092326
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
618 KB
Volume
28
Category
Article
ISSN
0006-2960

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## Abstract __The effects of site‐specific mutation of the axial cysteine (C357M) to a methionine residue in cytochrome P450cam on the enzyme’s coordination geometry and redox potential have been investigated. The absorption spectra of the haem centre in the C357M mutant of the enzyme showed close