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The stromal cell antigen CD248 (endosialin) is expressed on naive CD8+ human T cells and regulates proliferation

✍ Scribed by Debbie L. Hardie; Mathew J. Baldwin; Amy Naylor; Oliver J. Haworth; Tie Zheng Hou; Sian Lax; S. John Curnow; Nick Willcox; John MacFadyen; Clare M. Isacke; Christopher D. Buckley

Book ID: 108782894
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 893 KB
Volume: 133
Category: Article
ISSN: 0019-2805
DOI: 10.1111/j.1365-2567.2011.03437.x

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al