The stress-induced hyperthermia paradigm as a physiological animal model for anxiety: A review of pharmacological and genetic studies in the mouse

The infant mouse as a in vivo model for

The infant mouse as a in vivo model for the detection and study of DNA damage–induced changes in the liver

✍ Randall Reynolds; Sam Witherspoon; Tony Fox 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB

## Abstract The present work describes the use of the infant (4‐wk‐old) mouse as an animal model for the study of DNA damage–induced G~1~ checkpoint response, changes in p53 protein levels, and multiple gene expression changes after DNA damage has been induced in the liver. Hepatocytes in the infan