A novel stereospecific synthesis of (ยฑ)-
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Judith C. Buck; Frank Ellis; Peter C. North
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Article
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1982
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Elsevier Science
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French
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The reaction of the phosphonate 1 with the epoxyaldehyde 1 1s reported as the key step In a novel stereospeclfic synthesis of (+)-LTA4, methyl ester 1 The possible implication of the leukotrienes LTC4, D4 and E4 In Immediate hypersensitivity reactlons such as allergic asthma, has prompted much inte