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The stereoselective Birch reduction of pyrroles

✍ Scribed by Timothy J. Donohoe; Paul M. Guyo; Madeleine Helliwell


Book ID
104260423
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
246 KB
Volume
40
Category
Article
ISSN
0040-4039

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The Birch reduction of 3-substituted pyr
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Non-alkylated 3,4-dehydroprolines are obtained by diastereoselective protonation after Birch reduction of N-Boc-pyrrole carboxylic amides. Based on quantum chemical calculations the mechanism of asymmetric protonation is discussed.

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v