The stereocontrolled synthesis of 1,2-cis furanosyl nucleosides via a novel anomeric activation
✍ Scribed by Stephen Hanessian; Jose J. Condé; Boliang Lou
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 215 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Reoeirod 15 garch 1966) Some substituted groups at C-2 in the pyranose ring hare influence not only on the optical rotation (l-4) but also on the anomeric configuration of the pyranoses (5-9). 3,4,6-Tri-+cetyl-2-&trichloroacetyl-P\_P (5), 3,4,6-tri-pacetyl-2-gnitro-P\_p (6), and 3,4,6-tri-&acetyl-P\
A b&act: By employing ris-2.6-dimethylmorpboljnemethylene immonium tetmchloroaluminate (5) enamines 9 and 10, prepared from 4-tt-rt-butylpropiophenone and propiophenone with (R)-(-j2-(methoxymethyl)pyrrolidine (8). were converted to chiral Man&h bases Il.12 with nearly 100% ce; optical purity of the