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The stereochemistry of chromomycinone and a note on the benzoate rule

โœ Scribed by M. Miyamoto; K. Morita; Y. Kawamatsu; K. Kawashima; K. Nakanishi


Publisher
Elsevier Science
Year
1967
Tongue
French
Weight
599 KB
Volume
23
Category
Article
ISSN
0040-4020

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โœฆ Synopsis


Am--It

has been shown that chromomycinom can be rcprescntcd by the absolute con&urationa~ struEtlllt 1. Molecular rotation difkxu between the ratate and benzostc of secondary alcohols can be employed for deriving the rtnolute configuration.

CHROMOMYCI~~ONE (11,' GH,O,,

is the common aglycone of closely related antibiotics, chromomycin A,, A, and A,, the structures of which have recently been elucidated by the present authors .* The stereochemistry of this chromophore will be discussed in this paper.


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