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The stabilization of microtubules in isolated spindles by tubulin-colchicine complex

โœ Scribed by Hays, T. S. ;Salmon, E. D.

Book ID
102806049
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
822 KB
Volume
6
Category
Article
ISSN
0886-1544

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Tubulin-colchicine complex (TC) inhibits
Tubulin-colchicine complex (TC) inhibits microtubule depolymerization by a capping reaction exerted preferentially at the minus end
โœ Lawrence G. Bergen; Gary G. Borisy ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 444 KB

The effects of colchicine and tubulin-colchicine complex (TC) on microtubule depolymerization were studied using the axoneme-subunit system described previously [Bergen LG, Borisy GG; J Cell Biol 84:141-150, 1980]. This system allows the independent analysis of the polymerization kinetics at both th