The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos
β Scribed by Wright, Edwina; Hargrave, Murray R.; Christiansen, Jeffrey; Cooper, Leanne; Kun, Jutta; Evans, Timothy; Gangadharan, Uma; Greenfield, Andy; Koopman, Peter
- Book ID
- 109914923
- Publisher
- Nature Publishing Group
- Year
- 1995
- Tongue
- English
- Weight
- 834 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1061-4036
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## Abstract The testisβdetermining factor in the mouse is encoded by the __Sry__ gene on the Y chromosome. Transcripts of this gene have been shown previously to be present in the genital ridge at the beginning of gonadal differentiation (11.5 days post coitum) and in adult testis. In this study, R
Sry, the mammalian Y-linked testis determining gene, is a member of a family of genes known as Sox genes, which encode transcription factors related by a DNA-binding motif termed the HMG box. Sox genes are known to have diverse roles in vertebrate differentiation and development. We report here the