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The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus

✍ Scribed by Ruth Fritsch-Stork, Daniela Müllegger, Karl Skriner…


Book ID
120707566
Publisher
BioMed Central
Year
2006
Tongue
English
Weight
526 KB
Volume
8
Category
Article
ISSN
1478-6354

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✍ Eric L. Greidinger; Tal Gazitt; Kimberly F. Jaimes; Robert W. Hoffman 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 132 KB 👁 1 views

## Abstract ## Objective To identify and characterize human T cells reactive with heterogeneous nuclear RNP A2 (hnRNP A2) antigen, and to determine the ability of hnRNP‐reactive T cells to assist in the production of human autoantibodies. ## Methods T cells from patients with high serum levels o