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The sphingosine-1-phosphate derivative NHOBTD inhibits angiogenesis both in vitro and in vivo

✍ Scribed by Beom Seok Kim; Hyomi Park; Seung Hwan Ko; Won Koo Lee; Ho Jeong Kwon

Book ID
116302251
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
750 KB
Volume
413
Category
Article
ISSN
0006-291X

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## Abstract Integrins play an essential role in endothelial cell motility processes during angiogenesis and thus present interesting targets for the development of new anti‐angiogenic agents. Snake venoms naturally contain a variety of proteins that can affect integrin–ligand interactions. Recently