Ser-249TP53 mutation in tumour and plasm
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Katarzyna Szymańska; Olufunmilayo A. Lesi; Gregory D. Kirk; Omar Sam; Philippe T
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Article
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2004
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John Wiley and Sons
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French
⚖ 240 KB
## Abstract Hepatocellular carcinoma (HCC) is frequent in areas of high exposure to aflatoxin and high prevalence of HBV infection, such as western Africa and south‐east China. A selective mutation in __TP53__ (AGG→AGT at codon 249, Arg→Ser) has been identified as a hotspot in HCCs from such areas,