𝔖 Bobbio Scriptorium
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The specificity of surface membrane immunofluorescence in human malignant melanoma

✍ Scribed by M. G. Lewis; T. M. Phillips


Publisher
John Wiley and Sons
Year
1972
Tongue
French
Weight
604 KB
Volume
10
Category
Article
ISSN
0020-7136

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✦ Synopsis


Abstract

A study of membrane immunofluorescence on human malignant melanoma cells confirms previous preliminary reports indicating lack of significant cross‐reactivity with other melanoma sera, similar to that described in chemical carcinogen induced tumours. The importance of careful and critical appraisal of this technique is emphasized, and is supported by several other test systems, including cytotoxicity, demonstrating lack of cross‐reactivity. Multiple cross‐reactions with EB~3~ virus‐infected Burkitt lymphoma cells and glandular fever sera were clearly seen using the same methods of immunofluorescence and interpretation.


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