## Abstract Sera from melanoma patients, healthy donors, pregnant women and patients with types of tumors other than melanoma were tested on various melanoma lines as well as on a cultured brain tumor and adult skin fibroblasts, using a microimmune adherence test. Positive reactions against all cel
The specificity of surface membrane immunofluorescence in human malignant melanoma
β Scribed by M. G. Lewis; T. M. Phillips
- Publisher
- John Wiley and Sons
- Year
- 1972
- Tongue
- French
- Weight
- 604 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A study of membrane immunofluorescence on human malignant melanoma cells confirms previous preliminary reports indicating lack of significant crossβreactivity with other melanoma sera, similar to that described in chemical carcinogen induced tumours. The importance of careful and critical appraisal of this technique is emphasized, and is supported by several other test systems, including cytotoxicity, demonstrating lack of crossβreactivity. Multiple crossβreactions with EB~3~ virusβinfected Burkitt lymphoma cells and glandular fever sera were clearly seen using the same methods of immunofluorescence and interpretation.
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