The spatial distribution of currents in the receptor layer of the frog retina
β Scribed by W. Ehrhardt; Ch. Baumann
- Book ID
- 104741626
- Publisher
- Springer-Verlag
- Year
- 1977
- Tongue
- English
- Weight
- 710 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0340-1200
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β¦ Synopsis
Steady state patterns of currents flowing extracellularly in the receptor layer of the frog retina are used to work out an electrical model of vertebrate rods. The model can be thought of as a linear network consisting of resistances and current sources. The model predicts the axial spread of currents along the outside of the receptors. In addition, it predicts membrane voltages in light and darkness. If the dark-adapted receptors are assumed to have a uniform membrane with a specific resistance of 500 f~. cm 2, a single rod gives rise to an extracellular dark current of about 200 pa.
π SIMILAR VOLUMES
Voltage dependent potassium currents were recorded using the wholecell mode of the patch-clamp technique for the first time from endfeet of Muller cells dissociated from the frog retina. Recordings from intact cells and isolated endfeet indicate that the inward rectifier potassium channel is the dom