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The SOX8 Gene Is Located within 700 kb of the Tip of Chromosome 16p and Is Deleted in a Patient with ATR-16 Syndrome

✍ Scribed by Dietmar Pfeifer; Francis Poulat; Elke Holinski-Feder; Frank Kooy; Gerd Scherer


Book ID
115614981
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
262 KB
Volume
63
Category
Article
ISSN
0888-7543

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The cellular protooncogene MYC encodes a nuclear transcription factor that is involved in regulating important cellular functions, including cell cycle progression, differentiation, and apoptosis. Dysregulated MYC expression appears critical to the development of various types of malignancies, and t