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The SOX10 transcription factor: evaluation as a candidate gene for central and peripheral hereditary myelin disorders

✍ Scribed by V. Pingault; N. Bondurand; C. Le Caignec; S. Tardieu; The clinical E.N.B.D.D.; N. Lemort; O. Dubourg; E. Le Guern; M. Goossens; O. Boespflug-Tanguy


Book ID
106096292
Publisher
Springer
Year
2001
Tongue
English
Weight
205 KB
Volume
248
Category
Article
ISSN
0340-5354

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Sox10 acts as a tissue-specific transcri
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## Abstract Myelin basic protein (MBP) is one of the major components of the myelin sheath that insulates axons. In the central nervous system, MBP is synthesized by differentiating oligodendrocytes. The expression of MBP in oligodendrocytes is regulated mainly at the transcriptional level. The Sp1