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The source of androgenic activity in the African wood Funtumia latifolia: A steroid hormone formed by the action of fusarium solani

✍ Scribed by Anthony J. Smith; John W. Wells


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
349 KB
Volume
29
Category
Article
ISSN
0022-5142

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✦ Synopsis


Abstract

The wood of an African tree Funtumia latifolia had androgenic properties when mixed with diets fed to chicks. The androgenic principle has been identified tentatively as an hydroxyandrosta‐1,4‐dienedione but it is not identical with 12β‐hydroxyandrosta‐1,4‐diene‐3,17‐dione isolated previously from the leaves of a Halorrhena species in Cameroun or as a microbial metabolite of deoxycholic acid. The androgen is formed by metabolism of the steroidal alkaloids in F. latifolia by the saprophytic fungus Fusarium solani.