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The Solution to a Deep Stereochemical Conundrum: Studies toward the Tetrahydroisoquinoline Alkaloids

✍ Scribed by Collin Chan; Shengping Zheng; Bishan Zhou; Jinsong Guo; Richard M. Heid; Benjamin J. D. Wright; Samuel J. Danishefsky


Book ID
101565217
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
175 KB
Volume
45
Category
Article
ISSN
0044-8249

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Studies directed toward the total synthe
✍ Robert J. Heffner; Madeleine M. JoulliΓ© πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 289 KB

A highiy strained Il-memberedpara-ansa cyclopeptide, a potentialprecursor of the cyclopeptide alkaloid, nummularine-F, was made by cyclization of a pentafluorophenyl ester under catalytic hydrogenation conditions. This cyciization and the stereoselective synthesis of the acyclic activated ester f/am