To understand the structural requirements for the biological activity of endothelin peptides and to develop receptor selective endothelin analogues further, the solution structure of the bicyclic 21 amino acid residue vasoactive peptide, endothelin-1, has been determined in methanol-d Q /water using
The solution structure of some cobalamins determined by NMR-restrained molecular modelling
β Scribed by Christopher B. Perry; Kenneth L. Brown; Xiang Zou; Helder M. Marques
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 467 KB
- Volume
- 737
- Category
- Article
- ISSN
- 0022-2860
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Enduracidin and ramoplanin belong to the large family of cyclodepsipeptide antibiotics, highly effective against Gram-positive bacteria. The primary and 3D solution structure of ramoplanin is already well known, and the primary structure of enduracidin has been determined by a combination of chemica
The solution structure of an a-amylase inhibitor, tendamistat, calculated from nmr data with the distance geometry program DISMAN is subjected to restrained energy minimization. To study the influence of force field parametrizations and the convergence behavior of refinement algorithms, two differen