The TP53 gene has been extensively studied in patients with chronic myeloid leukemia (CML), both in chronic phase and in blast crisis. Mutations in the gene were found in up to 30% of the patients, especially among those in blast crisis. We report the results of an analysis of 29 blood samples from
✦ LIBER ✦
The SOCS-1 gene methylation in chronic myeloid leukemia patients
✍ Scribed by Ozden Hatirnaz; Umit Ure; Cem Ar; Cemaliye Akyerli; Teoman Soysal; Burhan Ferhanoğlu; Tayfun Özçelik; Ugur Ozbek
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 77 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0361-8609
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## RESULTS. At the time of CML diagnosis, 19 patients had TRFs within the age-Medical College, Tokyo, Japan. matched normal range (mean { 2 1 standard deviation [SD]) and the remaining 2 Department of Cell Biology and Neuroscience, 25 patients had TRFs shorter than the age-matched normal range (õ
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