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The small-molecule CDK inhibitor, SNS-032, enhances cellular radiosensitivity in quiescent and hypoxic non-small cell lung cancer cells

✍ Scribed by Kodym, Elisabeth; Kodym, Reinhard; Reis, Aimee E.; Habib, Amyn A.; Story, Michael D.; Saha, Debabrata


Book ID
119320099
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
934 KB
Volume
66
Category
Article
ISSN
0169-5002

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## Abstract In this study, we have characterized a panel of NSCLC cell lines with differential sensitivity to gefitinib for activating mutations in __egfr__, __pik3ca__, and __k‐ras__, and basal protein expression levels of PTEN. The __egfr__ mutant NSCLC cell line H1650 as well as the __egfr__ wil