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The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion

✍ Scribed by Goda, Yukiko; Geppert, Martin; Stevens, Charles F.; Südhof, Thomas C.


Book ID
109806846
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
282 KB
Volume
387
Category
Article
ISSN
0028-0836

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## Abstract **Background:** Rab3A, a member of the Rab3 small G protein family, regulates Ca^2+^‐dependent exocytosis of neurotransmitter. The cyclical activation and inactivation of Rab3A are essential for the Rab3A action in exocytosis. GDP‐Rab3A is activated to GTP‐Rab3A by Rab3 GDP/GTP exchange