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The Slug Mucosal Irritation (SMI) assay: A tool for the evaluation of nasal discomfort

โœ Scribed by Lenoir, Joke; Bachert, Claus; Remon, Jean-Paul; Adriaens, Els

Book ID
122457121
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
595 KB
Volume
27
Category
Article
ISSN
0887-2333

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New aspects of the Slug Mucosal Irritati
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โœ Joke Lenoir; Els Adriaens; Jean-Paul Remon ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 354 KB

## ABSTRACT Stinging, itching and/or burning (SIB) sensations cannot be detected by animal tests or __in vitro__ models. In the past, the Slug Mucosal Irritation (SMI) assay demonstrated a relation between an increased mucus production in slugs and an elevated incidence of SIB sensations in humans.