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The single-stranded DNA binding protein, Pur-α, binds HIV-1 TAR RNA and activates HIV-1 transcription

✍ Scribed by Lara G. Chepenik; Anna P. Tretiakova; Chavdar P. Krachmarov; Edward M. Johnson; Kamel Khalili


Book ID
117522949
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
298 KB
Volume
210
Category
Article
ISSN
0378-1119

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A complex between the Tat protein, encoded by human immunodeficiency virus type 1 (HIV-1), and the cellular protein, Pur␣, has been implicated in activation of the late promoter of JC virus (JCV) and in enhancement of JCV DNA replication. JCV is the causative agent of progressive multifocal leukoenc