✦ LIBER ✦
The simultaneous determination of caffeine, aspirin and paracetamol by principal components regression using automatic dilution and calibration
✍ Scribed by S. Dunkerley; M.J. Adams
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 972 KB
- Volume
- 33
- Category
- Article
- ISSN
- 1381-141X
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✦ Synopsis
The development of continuous and stepwise automatic dilution and calibration systems that enable analyte dilution and enhancement in multicomponent analyses are described. The continuous system has been used with a robot and the stepwise configuration integrated into a flow-injection analysis system. All analyses are performed using a UV/Visible diode-array detector and data analysis performed using principal components regression. Results of both systems are presented for the simultaneous determination of caffeine, aspirin and paracetamol in pharmaceutical formulations. 0 1997 Elsevier Science B.V.