✦ LIBER ✦
The simultaneous assay of riboflavin 5-phosphate sodium and other water-soluble vitamins in liquid multivitamin formulations by liquid chromatograph
✍ Scribed by F.L. Lam; A. Lowande
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 527 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0731-7085
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✦ Synopsis
A simple liquid chromatographic method for the simultaneous assay of niacinamide, pyridoxine, thiamine and riboflavin 5'-phosphate sodium in liquid multivitamin formulations is described. A novel aspect of the procedure is the conversion of the riboflavin 5'-phosphate sodium to riboflavin (vitamin B2) by reaction with alkaline phosphatase prior to quantitative HPLC. Excellent recovery, linearity and accuracy are obtained by the proposed method.