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The silent period after magnetic brain stimulation in generalized tetanus

โœ Scribed by Jason D. Warren; Thomas E. Kimber; Philip D. Thompson


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
101 KB
Volume
22
Category
Article
ISSN
0148-639X

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โœฆ Synopsis


The cortical silent period has not previously been studied in tetanus. Transcranial magnetic brain stimulation in a patient with generalized tetanus revealed enlarged electromyographic (EMG) responses and absence or reduction of the late phase of EMG silence following the motor evoked potential in sternomastoid and biceps brachii muscles. Following clinical recovery, the silent period returned to normal. This observation is interpreted as evidence of impaired inhibitory mechanisms at multiple levels of the nervous system, including the cortex, in generalized tetanus.


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## Abstract The silent period evoked by transcranial (TCS) and nerve stimulation was studied in the hand muscles in 13 patients with Huntington's disease and in 11 normal subjects. The duration of the silent period after TCS was longer in patients and correlated significantly with the severity of c