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The significance of the histochemical reaction for carboxyl groups of proteins in cartilage matrix

โœ Scribed by Morris J. Karnovsky; Marilyn S. Mann


Book ID
112391650
Publisher
Springer
Year
1961
Tongue
English
Weight
789 KB
Volume
2
Category
Article
ISSN
1432-119X

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Objective. To determine whether matrix metalloproteinases (MMPs) degrade cartilage oligomeric matrix protein (COMP) to produce fragments similar to those found in synovial fluid (SF) from patients with arthritis. Methods. COMP fragments were generated in vitro by treating (a) bovine articular carti