The significance of antibodies to cyclic citrullinated peptide, antikeratin antibodies, anti-perinuclear factor, rheumatoid factor isotypes and HLA shared epitope in prediction of erosive disease in early rheumatoid arthritis patients
✍ Scribed by J Vencovsky, L Sedova, S Machacek, J Gatterova, V Pesakova, J Kafkova…
- Book ID
- 120707806
- Publisher
- BioMed Central
- Year
- 2001
- Tongue
- English
- Weight
- 430 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1478-6354
- DOI
- 10.1186/ar171
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📜 SIMILAR VOLUMES
## Abstract ## Objective To examine the association between HLA–DRB1 alleles and the production of anti–cyclic citrullinated peptide (anti‐CCP) and rheumatoid factor (RF) autoantibodies in patients with rheumatoid arthritis (RA). ## Methods We studied 1,723 Caucasian RA patients enrolled in the
## Abstract ## Objective The shared epitope (SE)–containing HLA–DRB1 alleles represent the most significant genetic risk factor for rheumatoid arthritis (RA). Recent studies indicate that the SE alleles are associated with only RA that is characterized by the presence of anti–cyclic citrullinated