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The signaling protein Rho is necessary for vascular smooth muscle migration and survival but not for proliferation

โœ Scribed by Liu, Bo; Itoh, Hiroyuki; Louie, Otway; Kubota, Kenji; Kent, K.Craig


Book ID
123324143
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
693 KB
Volume
132
Category
Article
ISSN
0039-6060

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The state of the endothelial cell (EC) determines the nature of its control of vascular smooth muscle cell (vSMC) biology. Conditioned medium from postconfluent ECs inhibits vSMC proliferation, whereas subconfluent conditioned medium from the same ECs has a stimulatory effect. We and others have ide