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The signaling pathways linking to lysophosphatidic acid-promoted meiotic maturation in mice

โœ Scribed by Junko Komatsu; Shuji Yamano; Akira Kuwahara; Akira Tokumura; Minoru Irahara


Book ID
116718574
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
125 KB
Volume
79
Category
Article
ISSN
0024-3205

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In Xenopus oocytes, both sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) activate Ca2+-dependent oscillatory Cl- currents by acting through membrane-bound receptors. External application of 50 microM S1P elicited a long-lasting oscillatory current that continued over 30 min from the be