𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The short arm of chromosome 18 is a recurrent integration site of a supernumerary BCR/ABL gene fusion in chronic myeloid leukemia

✍ Scribed by Simone Metzke-Heidemann; Lana Harder; Stefan Gesk; Wolfgang Grimm; Reiner Siebert

Book ID
113513239
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
722 KB
Volume
179
Category
Article
ISSN
0165-4608

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Integration of amplified BCR/ABL fusion
Integration of amplified BCR/ABL fusion genes into the short arm of chromosome 17 as a novel mechanism of disease progression in chronic myeloid leukemia
✍ Simone Metzke-Heidemann; Lana Harder; Stefan Gesk; Robert Schoch; Stefan Jenisch 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 452 KB

## Abstract We describe the cases of two patients with Philadelphia chromosome–positive chronic myeloid leukemia (CML), in whom the extramedullary blastic phase developed during disease progression. The similar clinical presentations of these patients was accompanied by gain of identical secondary

Generation of the BCR/ABL fusion gene in
Generation of the BCR/ABL fusion gene in a Philadelphia chromosome-negative chronic myeloid leukaemia: insertion of 5.6 Mb of 9q34 into the BCR region of chromosome 22
✍ Laura Valle; Victoria Fernández; Concepción Pérez-Pons; Félix García Sánchez; Ja 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 165 KB

## Abstract This report describes a chronic myelogenous leukaemia patient with an apparently normal bone marrow karyotype but __BCR/ABL__ fusion‐gene‐positive. Commercial FISH probes showed an atypical pattern and the __BCR/ABL__ fusion transcript was detected by RT‐PCR, but not the reciprocal __AB