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The shared epitope hypothesis in rheumatoid arthritis: Evaluation of alternative classification criteria in a large UK Caucasian cohort

✍ Scribed by Ann W. Morgan; Lubna Haroon-Rashid; Stephen G. Martin; Hock-Chye Gooi; Jane Worthington; Wendy Thomson; Jennifer H. Barrett; Paul Emery


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
89 KB
Volume
58
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To determine whether the tumor necrosis factor Ξ± (__TNFA__) –308 guanine‐to‐adenosine polymorphism and/or the shared epitope (SE) is associated with radiographic damage in patients with early rheumatoid arthritis (RA). ## Methods The cohort consisted of 189 patients with