The SGOT/SGPT ratio—An indicator of alcoholic liver disease

✍ Scribed by Jerold A. Cohen; Marshall M. Kaplan

• Book ID: 112517090
• Publisher: Springer US
• Year: 1979
• Tongue: English
• Weight: 252 KB
• Volume: 24
• Category: Article
• ISSN: 0163-2116
• DOI: 10.1007/bf01324898

✦ Synopsis

The SGOT/SGPT ratio is significantly elevated in patients with alcoholic hepatitis and cirrhosis (2.85 +/- 0.2) compared with patients with postnecrotic cirrhosis (1.74 +/- 0.2), chronic hepatitis (1.3 +/- 0.17), obstructive jaundice (0.81 +/- 0.06) and viral hepatitis (0.74 +/- 0.07). An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70% of these patients compared with 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis and none with obstructive jaundice.