𝔖 Bobbio Scriptorium
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The sex chromosome that refused to die

✍ Scribed by John H. Malone; Brian Oliver

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
98 KB
Volume
30
Category
Article
ISSN
0265-9247

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Chromosomes that harbor dominant sex determination loci are predicted to erode over timeβ€”losing genes, accumulating transposable elements, degenerating into a functional wasteland and ultimately becoming extinct. The Drosophila melanogaster Y chromosome is fairly far along this path to oblivion. The few genes on largely heterochromatic Y chromosome are required for spermatocyte‐specific functions, but have no role in other tissues. Surprisingly, a recent paper shows that divergent Y chromosomes can substantially influence gene expression throughout the D. melanogaster genome.1 These results show that variation on Y has an important influence on the deployment of the genome. BioEssays 30:409–411, 2008. Β© 2008 Wiley Periodicals, Inc.

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