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The serum albumin-binding region of streptococcal protein G (BB) potentiates the immunogenicity of the G130–230 RSV-A protein

✍ Scribed by Christine Libon; Nathalie Corvaı̈a; Jean-François Haeuw; Thien Ngoc Nguyen; Stefan Ståhl; Jean-Yves Bonnefoy; Christine Andreoni


Book ID
117432987
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
943 KB
Volume
17
Category
Article
ISSN
0264-410X

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✍ Per-Åke Nygren; Margareta Eliasson; Lars Abrahmsén; Mathias Uhlén; Elisabeth Pal 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 699 KB

Streptococcal protein G is an IgG-binding receptor with a molecular weight of 63 kDa as predicted from the sequence of the corresponding gene. Here we show that a truncated recombinant protein of 23 kDa still has IgG-binding capacity and also interacts specifically with human serum albumin (HSA). Th