We studied the seroprevalence and transmission of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV8), among 215 Ugandan children, adolescents and young adults. We measured antibodies to a latent nuclear antigen (LANA) and a lytic cycle protein encoded by open reading frame (orf) 65. Infection with
The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma–associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission
✍ Scribed by Kedes, Dean H.; Operskalski, Eva; Busch, Michael; Kohn, Robert; Flood, Jennifer; Ganem, Don
- Book ID
- 109929828
- Publisher
- Nature Publishing Group
- Year
- 1996
- Tongue
- English
- Weight
- 912 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1078-8956
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Human herpesvirus 8 (HHV8), the etiological agent of Kaposi's sarcoma (KS), is transmitted mainly during childhood from seropositive family members, especially the mother, through saliva. The seroprevalence of HHV8 infection to a large extent reflects the distribution of KS, showing the same geograp
## Abstract We aimed to identify risk factors for Kaposi's sarcoma (KS) among HIV‐positive patients and behaviors associated with human Herpesvirus 8 (HHV‐8) infection, as well as to assess KS incidence and mortality rates longitudinally. To fulfill the first objective, a European case‐control stud