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The serine protease stratum corneum chymotryptic enzyme (kallikrein 7) is highly overexpressed in squamous cervical cancer cells

✍ Scribed by Alessandro D Santin; Stefania Cane'; Stefania Bellone; Eliana Bignotti; Michela Palmieri; Luis E De Las Casas; Juan J Roman; Simone Anfossi; Timothy O'Brien; Sergio Pecorelli

Book ID: 113959356
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 287 KB
Volume: 94
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2004.05.023

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The stratum corneum chymotryptic enzyme

The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells

✍ Hirotoshi Tanimoto; Lowell J. Underwood; Kazushi Shigemasa; Yan Yan M.S.; John C 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

## BACKGROUND. Proteases play essential roles in the process of tumor invasion and metastasis. The serine protease stratum corneum chymotryptic enzyme (SCCE) has been purified from human stratum corneum and is known to contribute to the cell shedding process by catalyzing the degradation of interce