Tumor-mediated down-regulation of MHC cl
✍
Young-Eun Choi; Ha-Nul Yu; Cheol-Hee Yoon; Yong-Soo Bae
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 242 KB
## Abstract In patients with cancer, DC express significantly lower amounts of MHC class II compared with those of normal individuals. However, the underlying mechanisms for this have not yet been fully defined. In the present study, we found that IL‐10 plays a major role in the tumor‐conditioned m