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The Sequence and Gene Characterization of a 400-kb Candidate Region for IDDM4 on Chromosome 11q13

✍ Scribed by Rebecca C.J. Twells; Michael L. Metzker; Sheryl D. Brown; Roger Cox; Caroline Garey; Holly Hammond; Patricia J. Hey; Elaine Levy; Yusuke Nakagawa; Michael S. Philips; John A. Todd; J.Fred Hess


Book ID
115615393
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
399 KB
Volume
72
Category
Article
ISSN
0888-7543

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A 3.3-kb Kpnl repeat unit within the tandem repeat locus (D4Z4) and its upstream 2.5-kb HinclllKpnl fragment of the facioscapulohumeral muscular dystrophy (FSHD) gene region at 4q35-qter were sequenced and characterized. The 3.3-kb Kpnl unit was 3303 bp in length and contained two homeodomain sequen