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The sensitive determination of nucleic acids using a fluorescence-quenching method

โœ Scribed by Zhen Jia; Jinghe Yang; Xia Wu; Changxia Sun; Fei Wang; Shufang Liu; Feng Wang


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
284 KB
Volume
21
Category
Article
ISSN
1522-7235

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In weak acidic medium, the anticancer antibiotics bleomycin A5 (BLMA5) and bleomycin A2 (BLMA2) bind with halofluorescein dyes, such as erythrosin (Ery), eosin Y (EY) and eosin B (EB), to form ion-association complexes, which causes fluorescence quenching of halofluorescein dyes. The quenching value