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The senescence-accelerated mouse (SAM-P8) as a model for the study of vascular functional alterations during aging

✍ Scribed by Silvia Lloréns; Raquel M Melero-Fernandez de Mera; Alejandro Pascual; Ana Prieto-Martín; Yolanda Mendizábal; Carlos de Cabo; Eduardo Nava; Joaquín Jordán

Book ID: 106361186
Publisher: Springer
Year: 2007
Tongue: English
Weight: 297 KB
Volume: 8
Category: Article
ISSN: 1389-5729
DOI: 10.1007/s10522-007-9108-4

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The infant mouse as a in vivo model for the detection and study of DNA damage–induced changes in the liver

✍ Randall Reynolds; Sam Witherspoon; Tony Fox 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB

## Abstract The present work describes the use of the infant (4‐wk‐old) mouse as an animal model for the study of DNA damage–induced G~1~ checkpoint response, changes in p53 protein levels, and multiple gene expression changes after DNA damage has been induced in the liver. Hepatocytes in the infan