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The self-cleavage of lariat-RNA

✍ Scribed by Peter Agback; Corine Glemarec; Lee Yin; Anders Sandström; Janez Plavec; Christian Sund; Shun-ichi Yamakage; Garimella Viswanadham; Bertrand Rousse; Nitin Puri; Jyoti Chattopadhyaya


Publisher
Elsevier Science
Year
1993
Tongue
French
Weight
319 KB
Volume
34
Category
Article
ISSN
0040-4039

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## Abstract Metal(II)‐induced hydrolysis of RNA produce products with 5′‐hydroxyls and 2′;3′‐cyclic phosphates at the ends. Ribozymes are RNA molecules that act as catalysts. Some ribozymes that cleave RNA also generate 5′‐hydroxyls and 2′;3′‐cyclic phosphates whereas others produces 5′‐phosphates

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## Abstract Structural representation of the interactions between RNase P RNA (top) and a precursor tRNA substrate (bottom). See RNase P RNA‐mediated Cleavage by Kirsebom and Trobro, pp. 189–200.