The selenium content of serum, whole blood and hair was measured by neutron activation analysis in dietetically treated patients with phenylketonuria (PKU) and maple-syrup-urine disease (MSUD). Follow-up studies showed a decrease of the serum selenium content and the glutathione peroxidase activity
The selenium state of healthy children
✍ Scribed by Ingrid Lombeck; K. Kasperek; H. D. Harbisch; L. E. Feinendegen; H. J. Bremer
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 433 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0340-6997
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✦ Synopsis
The selenium concentration of serum is age-dependent. The median value at birth (Yc = 50 X 10-9g/ml) amounts to half of the median value of adults (2= 102X 10-9g/m1). After a decrease in early infancy to 2=34 X 10-9g/ml it steadily increases to 2= 58 >( 10-gg/ml in the second half of the first year, to 2=82X 10-9g/ml in 1--5 year old children, and to = 92 X 10-gg/ml in school children. The activities of the selenium containing enzyme glutathione peroxidase of erythrocytes are also reduced in early infancy (2 = 7.2__+ 0.36 U37/g Hb), whereas the enzyme activities of cord blood erythrocytes (2 = 8.72 __+ 0.76 U37/g Hb) are in the same range as those of older children or adults. The selenium content of some commercially available milk formulas for infants are lower than those of human and cow's milk.
📜 SIMILAR VOLUMES
In 20 healthy infants and children, 5-20 months old, the Se intake was estimated by analysing food samples by instrumental neutron activation analysis. The intake was calculated by weighing the portions offered and actually consumed. The median Se content of the food amounted to 27 ng/ g wet weight