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The Selective Protection of Amino Functions in Aminoglycosides: A Review of Possible Approaches

โœ Scribed by A. van Schepdael; R. Busson; P. Claes


Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
409 KB
Volume
101
Category
Article
ISSN
0037-9646

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Signal peptides are N-terminal sequences that mediate the targeting and translocation of secreted or cell-surface proteins to the endoplasmic reticulum (ER) membrane. Because of the variability among signal peptides, traditional methods for predicting the effects of an amino acid substitution based