The role ofpyridine and of many substituted pyridines in Gif oxidation chemistry has been examined. In the presence of a suitable pyddine type base most of the solvent can be replaced by acetonitrile without diminishing the yield of oxidation products. The use of 4-tert-butylpyridine permits the iso
The selective functionalization of saturated hydrocarbons. Part 36. Stereoselectivity studies of Gif-type reactions
β Scribed by Derek H.R. Barton; Warinthorn Chavasiri
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 352 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
The stereoselectivity of various Gif-type reactions was evaluated using trans-l,4-dimethylcyclohexane as a chemical probe. The results revealed that these reactions were moderately stereoselective. The outcome of the reactions was preferentially formed in the more stable equatorial configuration.
π SIMILAR VOLUMES
The bromination of saturated hydrocarbons was studied in the GoAggln system using CBrCls and other polyhaloalkanes. This bromination reaction was compared to free radical processes by (i) evaluating the rates of reactions for a series of polyhaloalkanes, by (ii) measuring the selectivity of the diff